(Regional rule was Sudden Death, so that didn't factor into my deckbuilding at all) Had about a 70% winrate, not amazing but I was happy with that against Isobe.
If he plays H&K in bottom right (fairly common opener), don't play into bottom left, he's basically guaranteed a way to take Therion with Plus EVEN if you get Hildi/Nashu on the swap, and all the other cards are either Plus-able or just have weak right faces. My response was usually Seeker in top right, lose it to Crispy Grandpa, and then take Grandpa with either Avowed or whatever I got on the swap. Past that, it's just another Plus game.